Description

2-Bromo-3-Methylbutyric Acid is a versatile halogenated carboxylic acid building block of significant importance in advanced organic synthesis. Its unique structure, featuring both a reactive bromine atom and a carboxylic acid group, makes it a critical intermediate for constructing complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to introduce chiral centers and functionalized side chains into target compounds.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of chiral drugs and protease inhibitors.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators that require specific branched-chain acid motifs.
• Liquid Crystal & Polymer Chemistry: Serves as a monomer or precursor for specialty polymers and liquid crystal materials with tailored properties.
• Organic Synthesis Reagent: Employed in various name reactions for carbon-carbon bond formation and as a precursor for other functionalized derivatives like esters and amides.
• Flavor & Fragrance Industry: Intermediate for the synthesis of complex esters that contribute to specific flavor and aroma profiles.
• Research & Development: A valuable tool in academic and industrial R&D for exploring new synthetic methodologies and creating novel chemical entities.

Basic Information

Product Name	2-Bromo-3-Methylbutyric Acid
CAS No.	565-74-2
Molecular Formula	C5H9BrO2
Molecular Weight	181.03 g/mol
Synonyms	3-Methyl-2-bromobutanoic Acid; (±)-2-Bromo-3-methylbutyric Acid; α-Bromo-β-methylbutyric Acid; 2-Bromoisovaleric Acid; DL-2-Bromo-3-methylbutanoic Acid; NSC 406925; Bromomethylbutanoic Acid
EINECS	209-287-1

Quality Control

Our 2-Bromo-3-Methylbutyric Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment ensures the material meets the stringent requirements for research and commercial synthesis applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Recommended storage temperature is between 2°C and 8°C for long-term stability. Keep container tightly sealed when not in use to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.