Description

(1S,3R)-1,2,2-Trimethyl-1,3-Cyclopentanedicarboxylic Acid is a high-purity, chiral dicarboxylic acid derivative of significant interest in advanced organic synthesis. Its rigid, functionalized cyclopentane core makes it a valuable building block for pharmaceutical intermediates and fine chemicals, where stereochemical control is paramount. This compound is essential for research and development chemists and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors seeking to create complex, optically active molecules.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and other therapeutic areas.
• Asymmetric Catalyst Ligand Synthesis: Used to construct sophisticated ligand frameworks for metal-catalyzed asymmetric reactions.
• Fine Chemical Building Block: Employed in the research and production of complex organic molecules for agrochemicals, flavors, and fragrances.
• Polymer Modifier: Serves as a monomer or cross-linking agent to introduce rigidity and specific functional groups into specialty polymers.
• Academic & Industrial Research: A valuable tool for methodological development in organic synthesis and stereochemistry studies.

Basic Information

Product Name	(1S,3R)-1,2,2-Trimethyl-1,3-Cyclopentanedicarboxylic Acid
CAS No.	560-09-8
Molecular Formula	C10H16O4
Molecular Weight	200.23 g/mol
Synonyms	(1S,3R)-1,2,2-Trimethylcyclopentane-1,3-dicarboxylic Acid; (1S,3R)-TMCDA; (1S,3R)-1,2,2-Trimethyl-1,3-cyclopentanedicarboxylic acid; (1S,3R)-1,3-Cyclopentanedicarboxylic acid, 1,2,2-trimethyl-; (1S,3R)-HCA; Camphoric acid derivative; (1S,3R)-1,2,2-Trimethylcyclopentane-1,3-dicarboxylate
EINECS	Contact for details

Quality Control

Our (1S,3R)-1,2,2-Trimethyl-1,3-Cyclopentanedicarboxylic Acid is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral excess is provided with each shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to prevent absorption of atmospheric moisture, which may affect product quality.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.