Description

Nifuradene CAS NO 555-84-0 is a high-purity chemical compound, also known as 1-[(5-Nitrofurfurylidene)amino]hydantoin, valued for its role as a key intermediate in advanced synthesis. This compound is critical for ensuring the quality and consistency of downstream products in research and manufacturing. It is primarily utilized by the pharmaceutical and life science industries for the development of active pharmaceutical ingredients (APIs) and in specialized organic synthesis projects.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Research & Development: Used in academic and industrial laboratories for medicinal chemistry research and the development of novel therapeutic agents.
• Organic Synthesis: Acts as a specialized reagent or intermediate in multi-step synthetic routes for heterocyclic compounds.
• Chemical Reference Standard: Employed as a high-purity standard for analytical method development, validation, and quality control testing.

Basic Information

Product Name	Nifuradene
CAS No.	555-84-0
Molecular Formula	C8H6N4O5
Molecular Weight	238.16 g/mol
Synonyms	1-[(5-Nitrofurfurylidene)amino]hydantoin; 1-[(5-Nitro-2-furanyl)methylene]amino]-2,4-imidazolidinedione; Nitrofurantoin Impurity; Nitrofurantoin Related Compound; 5-Nitrofurfurylideneaminohydantoin; NFH; Nifuradene (USP); Contact for additional synonyms.
EINECS	209-108-4

Quality Control

Our Nifuradene is manufactured under a strict quality management system to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as assay, identity, and impurity profiles. We support compliance with cGMP and ICH guidelines for pharmaceutical intermediates, and specifications can be aligned with relevant pharmacopeial standards (e.g., USP) upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the material under an inert atmosphere for long-term stability and to minimize degradation.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.