Description

Proflavine is a synthetic acridine dye with significant antiseptic and bacteriostatic properties. This compound is valued for its ability to intercalate with nucleic acids, making it a crucial agent in microbiological research and clinical applications. It is primarily utilized by the pharmaceutical, biotechnology, and research sectors for its role as a topical antiseptic and a biological stain. Proflavine CAS NO 553-30-0 is supplied as a high-purity chemical to meet the stringent demands of these industries.

Application

• As an active ingredient in topical antiseptic and wound treatment formulations.
• Use as a biological stain for nucleic acid visualization in microbiological and histopathological laboratories.
• Research applications in studying DNA intercalation mechanisms and antimicrobial activity.
• Component in certain veterinary medicinal products for surface disinfection.
• Utilized in photodynamic therapy research due to its photosensitizing properties.
• Historical use in the treatment of burns and infected wounds, with ongoing research into modern applications.

Basic Information

Product Name	Proflavine
CAS No.	553-30-0
Molecular Formula	C13H11N3
Molecular Weight	209.25 g/mol
Synonyms	3,6-Diaminoacridine; Proflavine Hemisulfate Salt Precursor; Diaminoacridine; 3,6-Acridinediamine; 3,6-Diamino-10-acridinone (tautomer); Acrinol (base); Euflavine; Profanolum
EINECS	209-037-1

Quality Control

Our Proflavine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with key parameters including assay, impurity profile, and residual solvents. While not typically compendial, production can be aligned with general principles of GMP for pharmaceutical intermediates upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent absorption of atmospheric moisture, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	Orange to brownish-red crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.