Description

Isorhoifolin is a high-purity flavonoid glycoside, a key phytochemical compound with significant research and commercial interest. Its primary value lies in its potent biological activities, making it a sought-after standard and active ingredient for advanced applications. This product is essential for research institutions, pharmaceutical developers, and nutraceutical manufacturers focused on natural product chemistry and therapeutic discovery.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for quality control, method validation, and pharmacokinetic studies in drug development.
• Bioactivity & Mechanism Research: Employed in in-vitro and in-vivo studies to investigate anti-inflammatory, antioxidant, and potential anti-cancer properties.
• Natural Health Product Formulation: Incorporated as a key active ingredient in dietary supplements and functional foods targeting oxidative stress and metabolic health.
• Cosmeceutical Ingredient: Utilized in advanced skincare formulations for its purported anti-aging and skin-protective benefits.
• Chemical Synthesis Intermediate: Serves as a starting material or intermediate for the semi-synthesis of novel flavonoid derivatives.
• Analytical Testing: Acts as a critical standard for HPLC, LC-MS, and NMR analysis in botanical extract authentication and quantification.

Basic Information

Product Name	Isorhoifolin
CAS No.	552-57-8
Molecular Formula	C27H30O14
Molecular Weight	578.52 g/mol
Synonyms	Apigenin 7-O-neohesperidoside; Rhoifolin isomer; 5,7-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-7-yl 6-deoxy-α-L-mannopyranosyl-(1→2)-β-D-glucopyranoside; Apigenin-7-O-α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranoside; Lonicerin; Isorhoifolin (Apigenin 7-O-neohesperidoside); 4',5,7-Trihydroxyflavone-7-rutinoside
EINECS	209-012-5

Quality Control

Our Isorhoifolin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled in a low-humidity environment. For long-term storage, consider desiccant use and storage under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥98.0%
Loss on Drying	≤2.0%
Residue on Ignition	≤0.5%
Heavy Metals (as Pb)	≤20 ppm
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.