Description

Protohypericin CAS NO 548-03-8 is a naturally occurring naphthodianthrone derivative, recognized as a key biosynthetic precursor to the bioactive compound hypericin. This high-purity intermediate is of significant interest for research and development in advanced pharmaceutical and nutraceutical applications. It is primarily utilized by scientists and manufacturers in the life sciences sector for the synthesis of standardized botanical extracts and the investigation of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Critical precursor in the semi-synthesis of hypericin and related analogs for photodynamic therapy research.
• Reference Standard: Used as a certified reference material (CRM) in analytical laboratories for quality control of St. John's Wort (Hypericum perforatum) extracts and finished products.
• Biochemical Research: Serves as a tool compound in studies investigating the biosynthesis pathway of naphthodianthrones and their biological activities.
• Nutraceutical Development: Employed in the development and standardization of high-value botanical supplements targeting specific health endpoints.
• Academic Research: Utilized in university and institutional labs for pharmacological, photochemical, and metabolic studies.

Basic Information

Product Name	Protohypericin
CAS No.	548-03-8
Molecular Formula	C30H16O8
Molecular Weight	504.44 g/mol
Synonyms	Protohypericin; 1,3,4,6,8,13-Hexahydroxy-10,11-dimethylphenanthro[1,10,9,8-opqra]perylene-7,14-dione; Protoshypericin; Hypericin precursor; 4,4',5,5',7,7'-Hexahydroxy-2,2'-dimethylmesonaphthodianthrone
EINECS	Contact for details

Quality Control

Our Protohypericin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements for research and development applications. Certificates of Analysis (COA) detailing batch-specific results are provided to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Dark red to brown powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.