Description

[1R,5S,(-)]-4-Methyl-1-Isopropylbicyclo[3.1.0]Hexa-3-Ene-2-One is a high-purity, chiral bicyclic ketone of significant interest in advanced organic synthesis. Its unique and rigid molecular framework makes it a valuable chiral building block for constructing complex, stereochemically defined molecules. This compound is primarily sought after by pharmaceutical R&D and fine chemical sectors for applications in medicinal chemistry and the development of novel fragrances and flavors.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs) and complex natural product analogs.
• Asymmetric Synthesis: Utilized as a chiral scaffold or starting material for constructing molecules with specific three-dimensional configurations.
• Fragrance & Flavor Chemistry: Serves as a building block for creating novel, structurally unique aroma chemicals with specific olfactory properties.
• Agrochemical Research: Used in the development of new chiral pesticides and herbicides where stereochemistry impacts biological activity.
• Material Science Research: Investigated as a monomer or precursor for specialty polymers with tailored physical properties.
• Academic & Industrial R&D: Employed in methodological studies and discovery chemistry for new reactions and catalytic processes.

Basic Information

Product Name	[1R,5S,(-)]-4-Methyl-1-Isopropylbicyclo[3.1.0]Hexa-3-Ene-2-One
CAS No.	546-78-1
Molecular Formula	C10H14O
Molecular Weight	150.22 g/mol
Synonyms	(-)-4-Methyl-1-(1-methylethyl)bicyclo[3.1.0]hex-3-en-2-one; (1R,5S)-(-)-4-Methyl-1-isopropylbicyclo[3.1.0]hex-3-en-2-one; (-)-4-Methyl-1-isopropylbicyclo[3.1.0]hex-3-en-2-one; (1R,5S)-4-Methyl-1-isopropylbicyclo[3.1.0]hex-3-en-2-one; Bicyclo[3.1.0]hex-3-en-2-one, 4-methyl-1-(1-methylethyl)-, (1R,5S)-(-)-; (-)-Verbenone epoxide isomer
EINECS	Contact for details

Quality Control

Our [1R,5S,(-)]-4-Methyl-1-Isopropylbicyclo[3.1.0]Hexa-3-Ene-2-One is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC and GC, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing identity, purity, and enantiomeric excess are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Specific Rotation [α]	Contact for details
Refractive Index (n20D)	Contact for details
Density	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.