Description

4-Iodophenol is a versatile halogenated phenol derivative, serving as a critical building block in advanced organic synthesis. Its iodine substituent makes it a valuable intermediate for constructing complex molecules through cross-coupling reactions and functional group transformations. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, where precise chemical intermediates are required for developing new active ingredients and specialty polymers.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for thyroid hormone analogs and other iodine-containing therapeutics.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators that require halogenated phenolic structures.
• Material Science: Serves as a monomer or functionalizing agent for creating specialty polymers, liquid crystals, and advanced organic electronic materials.
• Cross-Coupling Reactions: An essential substrate in Suzuki, Heck, and other palladium-catalyzed coupling reactions to form biaryl and complex aromatic systems.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D labs for exploring new synthetic pathways and creating compound libraries.
• Dye & Pigment Intermediate: Used in the synthesis of certain iodine-complex dyes and colorants for specialized applications.

Basic Information

Product Name	4-Iodophenol
CAS No.	540-38-5
Molecular Formula	C6H5IO
Molecular Weight	220.01 g/mol
Synonyms	p-Iodophenol; 1-Hydroxy-4-iodobenzene; 4-Hydroxyiodobenzene; Phenol, 4-iodo-; Iodophenol; Para-iodophenol; 4-IP; UNII-3C3B668Q6R
EINECS	208-742-2

Quality Control

Our 4-Iodophenol is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR, to ensure it meets the high standards required for synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	92 - 96 °C
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.