Description

5-Nitroquinoline-2-Carboxylic Acid is a versatile nitro-substituted quinoline derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its bifunctional structure, which allows for selective chemical modifications at both the carboxylic acid and nitro groups, enabling the construction of complex molecular architectures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active pharmaceutical ingredients (APIs) and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel quinoline-based drug candidates, including potential antimicrobial and anticancer agents.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging the bioactive quinoline scaffold.
• Organic Light-Emitting Diodes (OLEDs): Serves as a starting material for the development of electron-transport or emissive layer materials in electronic displays.
• Coordination Chemistry & Ligand Design: The carboxylic acid group allows it to act as a chelating ligand for metal ions, useful in catalysis and material science.
• Dye and Pigment Industry: Employed as an intermediate for synthesizing specialized nitroquinoline-derived colorants and fluorescent markers.
• Academic & Industrial R&D: A valuable reagent for method development and exploring new reactions in heterocyclic and medicinal chemistry.

Basic Information

Product Name	5-Nitroquinoline-2-Carboxylic Acid
CAS No.	525-47-3
Molecular Formula	C10H6N2O4
Molecular Weight	218.17 g/mol
Synonyms	2-Quinolinecarboxylic acid, 5-nitro-; 5-Nitroquinaldic Acid; 5-Nitro-2-quinolinecarboxylic acid; 5-Nitroquinoline-2-carboxylic acid; 5-Nitro-2-carboxyquinoline; 525-47-3; 5-Nitroquinaldinic acid; 2-Carboxy-5-nitroquinoline
EINECS	Contact for details

Quality Control

Our 5-Nitroquinoline-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under dry conditions. For long-term storage, consider using an inert atmosphere to minimize oxidation.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	255 - 260 °C
Loss on Drying	≤ 1.0 %
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.