Description

Testosterone Hemisuccinate is a chemically modified ester derivative of the primary male androgen, testosterone. This modification enhances its solubility profile, making it a crucial intermediate in the development of advanced pharmaceutical formulations. It is primarily utilized by research institutions and pharmaceutical manufacturers in the development of hormone replacement therapies, performance-enhancing compounds, and other specialized medicinal products. The compound offers a versatile building block for creating prodrugs with tailored pharmacokinetic properties.

Application

• Pharmaceutical Intermediate: A key starting material or intermediate in the synthesis of injectable testosterone formulations and other androgen-based therapeutics.
• Research & Development: Used in biochemical and pharmacological research to study androgen receptor mechanisms, hormone metabolism, and the development of new steroid-based drugs.
• Prodrug Synthesis: The hemisuccinate ester group serves as a promoiety to improve the water solubility and bioavailability of parent testosterone in prodrug design.
• Reference Standard: Serves as a high-purity chemical reference standard in analytical laboratories for quality control and method validation (HPLC, MS).
• Veterinary Pharmaceuticals: Employed in the development of hormonal treatments for animals in veterinary medicine.

Basic Information

Product Name	Testosterone Hemisuccinate
CAS No.	521-15-3
Molecular Formula	C23H32O5
Molecular Weight	388.50 g/mol
Synonyms	Testosterone 17β-Hemisuccinate; Androst-4-en-17β-ol-3-one 17-Hemisuccinate; 17β-Hydroxyandrost-4-en-3-one 17-Hemisuccinate; Testosterone Succinate; NSC 113193; Testosterone Hydrogen Succinate; Testosterone 17-Hemisuccinate
EINECS	208-310-5

Quality Control

Our Testosterone Hemisuccinate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including identification (IR, HPLC), assay (HPLC), and control of related substances to ensure high purity and consistency. Certificates of Analysis (COA) detailing all test results are provided with every shipment. We can supply material compliant with various in-house specifications tailored for research or GMP starting material applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.