Description

4-[(R)-1,2,2-Trimethylcyclopentyl]Benzoic Acid is a chiral, substituted benzoic acid derivative characterized by its unique cyclopentyl structure. This compound is a valuable intermediate and building block in advanced organic synthesis, prized for its ability to impart specific stereochemistry and structural complexity to target molecules. It is primarily utilized by pharmaceutical, agrochemical, and specialty chemical research and development teams for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for non-steroidal anti-inflammatory drugs (NSAIDs) and other therapeutic agents.
• Agrochemical Synthesis: Used as a building block for developing advanced pesticides, herbicides, and plant growth regulators where specific stereochemistry is crucial for bioactivity.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of specialty organic compounds for electronic applications, including liquid crystal displays and organic light-emitting diodes.
• Fragrance & Flavor Chemistry: Acts as an intermediate for creating complex aroma chemicals and flavoring agents due to its structurally constrained, terpene-like backbone.
• Asymmetric Catalyst Ligand: The chiral framework can be utilized to develop novel ligands for asymmetric catalysis in fine chemical manufacturing.
• Academic & Industrial R&D: Employed in chemical research for methodological studies, total synthesis projects, and the exploration of new chemical entities.

Basic Information

Product Name	4-[(R)-1,2,2-Trimethylcyclopentyl]Benzoic Acid
CAS No.	509-02-4
Molecular Formula	C15H20O2
Molecular Weight	232.32 g/mol
Synonyms	(R)-4-(1,2,2-Trimethylcyclopentyl)benzoic acid; Benzoic acid, 4-[(1R)-1,2,2-trimethylcyclopentyl]-; Ambrox; (R)-Ambrox; (R)-Ambroxide precursor; (R)-(-)-4-(1,2,2-Trimethylcyclopentyl)benzoic acid; (R)-Labdanolic acid derivative; (R)-Trimethylcyclopentylbenzoic acid
EINECS	Contact for details

Quality Control

Our 4-[(R)-1,2,2-Trimethylcyclopentyl]Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure high chemical purity, correct stereochemistry, and consistent performance. We provide detailed Certificates of Analysis (COA) with each shipment, documenting key parameters such as assay, enantiomeric excess, and impurity profiles. Our quality commitment supports applications requiring GMP-grade intermediates and research-standard materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); protect from humidity and store under an inert atmosphere if specified for long-term storage. Keep away from incompatible materials such as strong oxidizing agents, strong bases, and strong acids.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% (R)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.