Description

Nitrofurantoin Sodium is the sodium salt derivative of the broad-spectrum antimicrobial agent nitrofurantoin. This compound is a critical pharmaceutical intermediate valued for its enhanced solubility and bioavailability compared to the parent nitrofurantoin. It is primarily utilized in the synthesis of finished dosage forms for the treatment of urinary tract infections, serving the needs of pharmaceutical manufacturers and advanced research institutions globally.

Application

• Pharmaceutical Active Ingredient (API) Synthesis: Primary use in the manufacturing of finished antimicrobial drugs.
• Urinary Tract Infection (UTI) Therapeutics: Key intermediate for formulating oral suspensions, capsules, and tablets targeting gram-positive and gram-negative bacteria.
• Veterinary Medicine: Used in the development of antimicrobial treatments for animals.
• Research & Development: Serves as a reference standard and building block in microbiological and pharmacological research.
• Controlled-Release Formulations: Employed in the development of advanced drug delivery systems to optimize dosing regimens.

Basic Information

Product Name	Nitrofurantoin Sodium
CAS No.	54-87-5
Molecular Formula	C8H6N4NaO5
Molecular Weight	261.15 g/mol
Synonyms	Nitrofurantoin Sodium Salt; Sodium Nitrofurantoin; 1-[[(5-Nitro-2-furanyl)methylene]amino]-2,4-imidazolidinedione Sodium Salt; Furadantin Sodium; (E)-1-[(5-Nitrofuran-2-yl)methylideneamino]imidazolidine-2,4-dione Sodium Salt; N-(5-Nitro-2-furfurylidene)-1-aminohydantoin Sodium Salt; Nitrofurantoin Na
EINECS	200-214-6

Quality Control

Our Nitrofurantoin Sodium is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which can affect stability and potency.

Specification

Item	Specification
Appearance	Yellow to orange-yellow crystalline powder
Identification (IR)	Conforms to standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 2.0%
Microbial Limits	Meets Ph. Eur. / USP requirements

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.