Description

n-Acetyl-5-Aminosalicylic Acid is a key pharmaceutical intermediate and derivative of mesalazine (5-aminosalicylic acid). This compound matters for its role in the synthesis of advanced drug formulations, offering enhanced stability and targeted delivery properties. It is primarily needed by manufacturers in the pharmaceutical industry for producing treatments for inflammatory bowel diseases, as well as by research institutions developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Critical for the synthesis of prodrugs and targeted-release formulations of 5-aminosalicylic acid (mesalazine).
• Active Pharmaceutical Ingredient (API) Manufacturing: Used in the production of medications for ulcerative colitis and Crohn's disease.
• Research & Development: Serves as a standard or building block in medicinal chemistry for developing new anti-inflammatory agents.
• Chemical Synthesis: Acts as a protected or modified form of 5-ASA for further chemical transformations in organic synthesis.
• Analytical Reference Standard: Employed in quality control laboratories for HPLC, LC-MS, or other analytical method development and validation.

Basic Information

Product Name	n-Acetyl-5-Aminosalicylic Acid
CAS No.	51-59-2
Molecular Formula	C9H9NO4
Molecular Weight	195.17 g/mol
Synonyms	5-Acetamidosalicylic Acid; N-Acetyl-5-ASA; N-Acetylmesalamine; 5-(Acetylamino)-2-hydroxybenzoic Acid; Acetyl-5-aminosalicylic Acid; 5-Acetamido-2-hydroxybenzoic Acid; 2-Hydroxy-5-acetamidobenzoic Acid; N-Acetyl-5-aminosalicylate
EINECS	200-097-7

Quality Control

Our n-Acetyl-5-Aminosalicylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.