Description

5'-Amino-2'-Hydroxyacetophenone is a versatile aromatic ketone derivative that serves as a critical building block in advanced organic synthesis. Its bifunctional nature, featuring both an amino and a hydroxyl group ortho to the carbonyl, makes it a valuable precursor for constructing complex heterocyclic systems and fine chemicals. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key starting material for the synthesis of various drug candidates, particularly those with benzoxazole or quinoline scaffolds.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators.
• Dye and Pigment Manufacturing: Serves as a precursor for azo dyes and other complex colorants.
• Coordination Chemistry: Acts as a chelating ligand for metal ions in catalyst design and material science.
• Fine Chemical Production: Intermediate for flavors, fragrances, and other high-value specialty chemicals.
• Research & Development: Utilized in academic and industrial R&D for novel compound library synthesis and method development.

Basic Information

Product Name	5'-Amino-2'-Hydroxyacetophenone
CAS No.	50-80-6
Molecular Formula	C8H9NO2
Molecular Weight	151.16 g/mol
Synonyms	2'-Hydroxy-5'-aminoacetophenone; 1-(2-Hydroxy-5-aminophenyl)ethanone; 5-Amino-2-hydroxyacetophenone; 2-Acetyl-4-aminophenol; 4-Amino-2-hydroxyacetophenone; 2-Hydroxy-5-aminoacetophenone; o-Hydroxy-p-aminoacetophenone
EINECS	200-064-4

Quality Control

Our 5'-Amino-2'-Hydroxyacetophenone is manufactured under a strict quality management system. Each batch is subjected to comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates for GMP or research purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Yellow to brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	138°C - 142°C
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.