Description

2H-Pyran-4-Carboxylicacid,2-Ethoxy-3,4-Dihydro-,Ethylester,(2S,4S)-(9Ci) CAS NO 497161-72-5 is a high-purity, stereochemically defined chiral intermediate of significant importance in advanced organic synthesis. Its value lies in its precise molecular architecture, which is critical for constructing complex molecules with specific biological activity. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of potential drug candidates, particularly in medicinal chemistry programs.
• Asymmetric Synthesis: Utilized in catalytic and stoichiometric asymmetric reactions to introduce stereogenic centers with high enantiomeric purity.
• Fine Chemical Production: Acts as a precursor for the manufacture of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Academic & Industrial R&D: Used in research laboratories for method development and exploring new synthetic pathways in heterocyclic chemistry.
• Agrochemical Synthesis: Potential intermediate in the development of chiral active ingredients for crop protection agents.
• Material Science Research: Investigated as a monomer or precursor for novel polymers with specific optical or structural properties.

Basic Information

Product Name	2H-Pyran-4-Carboxylicacid,2-Ethoxy-3,4-Dihydro-,Ethylester,(2S,4S)-(9Ci)
CAS No.	497161-72-5
Molecular Formula	C10H16O4
Molecular Weight	200.23 g/mol
Synonyms	(2S,4S)-2-Ethoxy-3,4-dihydro-2H-pyran-4-carboxylic acid ethyl ester; Ethyl (2S,4S)-2-ethoxy-3,4-dihydro-2H-pyran-4-carboxylate; 2-Ethoxy-3,4-dihydro-2H-pyran-4-carboxylic Acid Ethyl Ester, (2S,4S)-; (4S,6S)-6-Ethoxy-5,6-dihydro-2H-pyran-2-carboxylic acid ethyl ester; 497161-72-5; A chiral dihydropyran carboxylate ester
EINECS	Contact for details

Quality Control

Our production of this chiral intermediate adheres to strict quality protocols to ensure batch-to-batch consistency and high enantiomeric purity, which is paramount for synthetic applications. Quality is verified through advanced analytical techniques including Chiral HPLC and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity (enantiomeric excess), and identity is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be sensitive to moisture and prolonged exposure to air; keep container tightly sealed when not in use.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% e.e.
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.