Description

n-(2-Aminoethyl)-2,2,2-trifluoroacetamide hydrochloride is a specialized organic salt featuring a reactive aminoethyl group and a trifluoroacetamide moiety, making it a valuable building block for advanced chemical synthesis. This compound is critical for researchers and manufacturers requiring high-purity intermediates to develop novel pharmaceuticals and agrochemicals. It is primarily utilized by fine chemical and pharmaceutical R&D departments for creating active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring trifluoromethyl groups for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, where the fluorine atoms contribute to improved efficacy and environmental persistence.
• Peptide Modification & Linker Chemistry: Serves as a versatile reagent for introducing the trifluoroacetamide protecting group or as a functionalized linker in peptide and bioconjugate chemistry.
• Material Science Research: Employed in the creation of specialty polymers and coatings, where its unique structure can impart specific chemical resistance or surface properties.
• Chemical Biology Probes: Acts as a building block for synthesizing molecular probes and diagnostic agents used in biochemical research and assay development.

Basic Information

Product Name	n-(2-Aminoethyl)-2,2,2-Trifluoroacetamide Hydrochloride
CAS No.	496946-73-7
Molecular Formula	C4H8F3N2O·HCl
Molecular Weight	208.57 g/mol
Synonyms	2,2,2-Trifluoro-N-(2-aminoethyl)acetamide hydrochloride; N1-(2-Aminoethyl)-2,2,2-trifluoroacetamide hydrochloride; 2,2,2-Trifluoroacetamidoethylamine hydrochloride; 2-(2,2,2-Trifluoroacetamido)ethylammonium chloride; N-(2-Aminoethyl)trifluoroacetamide hydrochloride; TFAEA·HCl; 2-Aminoethyltrifluoroacetamide hydrochloride
EINECS	Contact for details

Quality Control

Our n-(2-Aminoethyl)-2,2,2-trifluoroacetamide hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and titration methods, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere or with appropriate desiccants to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.