Description

{[3-(2-Methoxyphenyl)-4-Oxo-2-(Trifluoromethyl)-4H-Chromen-7-Yl]Oxy}Acetonitrile is a high-value, functionalized chromene derivative designed for advanced chemical synthesis. This compound matters as a critical pharmaceutical intermediate and organic building block, offering a unique trifluoromethyl-substituted chromene scaffold for developing novel active ingredients. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to incorporate complex heterocyclic structures into new molecules.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, or cancer.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where the trifluoromethyl group can enhance biological activity and environmental stability.
• Organic Light-Emitting Diode (OLED) Materials: Acts as a building block for electron-transport or emissive layer materials in display and lighting technologies.
• Fluorescent Probe & Dye Synthesis: The chromene core is utilized to create specialized fluorescent markers for biochemical sensing and imaging applications.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies in organic chemistry and heterocyclic compound synthesis.
• Material Science Additive: Investigated for use in polymers and advanced coatings to impart specific optical or surface properties.

Basic Information

Item	Details
Product Name	{[3-(2-Methoxyphenyl)-4-Oxo-2-(Trifluoromethyl)-4H-Chromen-7-Yl]Oxy}Acetonitrile
CAS No.	496037-22-0
Molecular Formula	C20H14F3NO4
Molecular Weight	389.33 g/mol
Synonyms	7-[(Cyanomethoxy)]-3-(2-methoxyphenyl)-2-(trifluoromethyl)-4H-chromen-4-one; 2-(Trifluoromethyl)-3-(2-methoxyphenyl)-4-oxo-4H-chromen-7-yloxyacetonitrile; (7-Oxy-3-(2-methoxyphenyl)-4-oxo-2-(trifluoromethyl)-4H-chromen)acetonitrile; Chromene-7-oxyacetonitrile derivative; TFMC Intermediate
EINECS	Contact for details

Quality Control

Our {[3-(2-Methoxyphenyl)-4-Oxo-2-(Trifluoromethyl)-4H-Chromen-7-Yl]Oxy}Acetonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure compliance with exacting R&D and process chemistry standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere if necessary to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.