Description

4-(6-Chloro-Pyridazin-3-Yl)-Piperazine-1-Carboxylic Acid tert-Butyl Ester is a high-value, protected piperazine-pyridazine hybrid building block designed for advanced organic synthesis. This compound matters because it provides a versatile and reactive scaffold for constructing complex molecules, particularly in pharmaceutical research and development. It is primarily needed by medicinal chemists and process R&D teams in the pharmaceutical, agrochemical, and fine chemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and cardiovascular therapeutic areas.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies due to its modifiable piperazine and chloropyridazine moieties.
• Agrochemical Synthesis: Serves as a precursor for developing new herbicides, fungicides, or insecticides with specific biological activity.
• Chemical Biology Probe Development: Utilized in creating tool compounds for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring complex heterocyclic architectures.
• Library Synthesis for High-Throughput Screening: Enables the rapid generation of diverse compound libraries for biological screening campaigns.

Basic Information

Product Name	4-(6-Chloro-Pyridazin-3-Yl)-Piperazine-1-Carboxylic Acid tert-Butyl Ester
CAS No.	492431-11-5
Molecular Formula	C14H19ClN4O2
Molecular Weight	310.78 g/mol
Synonyms	tert-Butyl 4-(6-chloropyridazin-3-yl)piperazine-1-carboxylate; 1-Boc-4-(6-chloropyridazin-3-yl)piperazine; 4-(6-Chloro-3-pyridazinyl)-1-piperazinecarboxylic acid 1,1-dimethylethyl ester; N-Boc-4-(6-chloropyridazin-3-yl)piperazine; 1-(tert-Butoxycarbonyl)-4-(6-chloropyridazin-3-yl)piperazine; 492431-11-5; 4-(6-Chloro-pyridazin-3-yl)-piperazine-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our 4-(6-Chloro-Pyridazin-3-Yl)-Piperazine-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity building blocks for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.