Description

(5S)-5-Phenyl-2-Morpholinone Hydrochloride is a high-purity chiral building block and pharmaceutical intermediate. This compound is critical for the synthesis of enantiomerically pure molecules, offering researchers and manufacturers a reliable source for complex chemical scaffolds. It is primarily utilized by the pharmaceutical, agrochemical, and fine chemical industries for research, development, and production processes.

Application

• Pharmaceutical Intermediate: Key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and other therapeutic agents.
• Asymmetric Synthesis: Serves as a versatile building block for constructing complex molecules with high stereochemical control in medicinal chemistry.
• Agrochemical Research: Used in the development of novel, enantiopure pesticides and herbicides where specific stereochemistry is required for biological activity.
• Catalyst and Ligand Development: Potential precursor for the synthesis of novel chiral catalysts and ligands used in homogeneous catalysis.
• Academic & Industrial R&D: A valuable reagent for synthetic organic chemists in universities and corporate R&D laboratories exploring new chemical entities.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals and advanced materials requiring precise molecular architecture.

Basic Information

Product Name	(5S)-5-Phenyl-2-Morpholinone Hydrochloride
CAS No.	491833-36-4
Molecular Formula	C₁₀H₁₂ClNO₂
Molecular Weight	213.66 g/mol
Synonyms	(5S)-5-Phenylmorpholin-2-one hydrochloride; (S)-5-Phenyl-2-morpholinone hydrochloride; 2-Morpholinone, 5-phenyl-, hydrochloride, (5S)-; (S)-5-Phenylmorpholine-2-one HCl; 491833-36-4; (5S)-5-Phenyl-3,4-dihydro-2H-1,4-oxazin-2-one hydrochloride
EINECS	Contact for details

Quality Control

Our (5S)-5-Phenyl-2-Morpholinone Hydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques, including HPLC, NMR, and chiral analysis, to verify identity, potency, and enantiomeric excess. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment, supporting compliance in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.