Description

Cyclobutanecarboxylic Acid, 2-[(Aminocarbonyl)Amino]-, (1R,2S)-Rel- (9Ci) is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. Its core value lies in its unique bicyclic structure and functional groups, which make it a critical intermediate for constructing complex molecular architectures with precise spatial orientation. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, particularly where specific stereochemistry is crucial for biological activity.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), especially for candidates targeting central nervous system (CNS) disorders, metabolic diseases, and anti-infective agents.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the specific stereochemistry of the molecule can influence efficacy and environmental selectivity.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing novel chiral ligands and organocatalysts used in enantioselective synthesis.
• Peptidomimetic Research: Its structure is valuable for creating conformationally constrained peptide analogs in medicinal chemistry programs.
• Chemical Biology Probe Development: Employed in the synthesis of molecular probes to study enzyme mechanisms and protein-ligand interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high stereochemical purity.

Basic Information

Item	Detail
Product Name	Cyclobutanecarboxylic Acid, 2-[(Aminocarbonyl)Amino]-, (1R,2S)-Rel- (9Ci)
CAS No.	488862-92-6
Molecular Formula	C6H10N2O3
Molecular Weight	158.16 g/mol
Synonyms	(1R,2S)-rel-2-(Aminocarbonylamino)cyclobutanecarboxylic Acid; (1R,2S)-rel-2-Ureidocyclobutanecarboxylic Acid; rel-(1R,2S)-2-Carbamoylaminocyclobutanecarboxylic Acid; 2-Ureidocyclobutanecarboxylic Acid, (1R,2S)-rel-; Cyclobutanecarboxylic acid, 2-[(aminocarbonyl)amino]-, (1R,2S)-rel-; 488862-92-6; (1R,2S)-rel-2-Aminocarbonylaminocyclobutanecarboxylic Acid
EINECS	Contact for details

Quality Control

Our Cyclobutanecarboxylic Acid, 2-[(Aminocarbonyl)Amino]-, (1R,2S)-Rel- (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting customer specifications and research-grade standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.