Description

4-[4-(Morpholin-4-Yl)-3-Nitrophenyl]-1,2-Dihydrophthalazin-1-One is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound matters as a critical building block in the synthesis of novel therapeutic agents, particularly within kinase inhibitor research and development. It is primarily needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in developing targeted cancer therapies and other specialized medicinal compounds.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the multi-step synthesis of potent kinase inhibitors and other targeted small-molecule drugs.
• Oncology Research: Used in the discovery and development of novel anti-cancer compounds, leveraging its specific molecular scaffold for binding to enzyme active sites.
• Biochemical Tool Compound: Employed in academic and industrial research as a reference standard or a probe to study specific biological pathways and enzyme functions.
• Medicinal Chemistry: Provides a versatile core structure for structure-activity relationship (SAR) studies and lead optimization programs in drug discovery.
• Custom Synthesis: Supplied to fine chemical companies for the contract manufacturing of proprietary Active Pharmaceutical Ingredients (APIs) or advanced intermediates.
• Process Development: Utilized in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.

Basic Information

Product Name	4-[4-(Morpholin-4-Yl)-3-Nitrophenyl]-1,2-Dihydrophthalazin-1-One
CAS No.	488137-27-5
Molecular Formula	C18H16N4O4
Molecular Weight	352.35 g/mol
Synonyms	4-[4-(4-Morpholinyl)-3-nitrophenyl]-1(2H)-phthalazinone; 4-(4-Morpholino-3-nitrophenyl)phthalazin-1(2H)-one; 1(2H)-Phthalazinone, 4-[4-(4-morpholinyl)-3-nitrophenyl]-; 488137-27-5; UNII-6Q4K3G2H8H; 6Q4K3G2H8H; 4-(4-Morpholin-4-yl-3-nitrophenyl)-2H-phthalazin-1-one; 4-(4-Morpholino-3-nitrophenyl)-1,2-dihydrophthalazin-1-one
EINECS	Contact for details

Quality Control

Every batch of 4-[4-(Morpholin-4-Yl)-3-Nitrophenyl]-1,2-Dihydrophthalazin-1-One is manufactured under strict quality management systems. Our products undergo rigorous quality testing to ensure compliance with industry standards for advanced pharmaceutical intermediates. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from degradation.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.