Description

2H-Pyran, 2-(4-Bromo-3-Fluorophenoxy)Tetrahydro- is a specialized fluorinated and brominated heterocyclic building block of significant interest in advanced organic synthesis. Its unique molecular architecture, featuring both halogen substituents and a tetrahydro-2H-pyran ring, makes it a valuable intermediate for constructing complex molecules with tailored properties. This compound is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and crop protection agent discovery. The CAS number for this compound is 485832-11-9.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for introducing halogenated aromatic motifs.
• Agrochemical Synthesis: Used in the discovery and production of novel herbicides, fungicides, and insecticides, where the bromo-fluorophenoxy group can enhance biological activity.
• Ligand and Catalyst Development: Acts as a precursor for creating specialized ligands in asymmetric catalysis or as a building block for functional materials.
• Organic Electronic Materials: Potential use in the synthesis of monomers or intermediates for specialty polymers and advanced materials research.
• Chemical Biology Probes: Utilized in the design of molecular probes and tags for studying biological systems due to its halogen handles for further functionalization.

Basic Information

Product Name	2H-Pyran, 2-(4-Bromo-3-Fluorophenoxy)Tetrahydro-
CAS No.	485832-11-9
Molecular Formula	C11H12BrFO2
Molecular Weight	275.12 g/mol
Synonyms	2-(4-Bromo-3-fluorophenoxy)tetrahydro-2H-pyran; Tetrahydro-2H-pyran-2-yl 4-bromo-3-fluorophenyl ether; 4-Bromo-3-fluoro-1-((tetrahydro-2H-pyran-2-yl)oxy)benzene; 2-(4-Bromo-3-fluorophenoxy)oxane; 2-(4-Bromo-3-fluorophenoxy)tetrahydropyran; THP ether of 4-bromo-3-fluorophenol
EINECS	Contact for details

Quality Control

Our 2H-Pyran, 2-(4-Bromo-3-Fluorophenoxy)Tetrahydro- is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting the specific results for your quality assurance and regulatory needs. Our commitment is to deliver high-purity building blocks that meet the exacting standards of research and process chemistry.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (typically 15-25°C). This compound may be sensitive to strong alkali and fluoride ions; avoid contact with such materials. Keep container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white solid or clear to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥95.0% (Typical 97-99%)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.