Description

8-Oxa-3-Azabicyclo[3.2.1]Octane-3-Acetonitrile(9Ci) is a high-purity, advanced pharmaceutical intermediate featuring a unique bridged bicyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of complex drug candidates. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in medicinal chemistry, process development, and the production of specialized fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new therapeutic agents, especially those targeting the central nervous system.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing complex molecular architectures in drug discovery programs.
• Process Chemistry & Scale-up: Used in the optimization and commercial-scale synthesis of target drug molecules requiring its specific bicyclic framework.
• Fine Chemical Synthesis: Employed in the production of specialized, high-value chemicals for advanced material science and agrochemical research.
• Contract Manufacturing (CMO): Supplied to contract development and manufacturing organizations (CDMOs) for cGMP production of client APIs.

Basic Information

Product Name	8-Oxa-3-Azabicyclo[3.2.1]Octane-3-Acetonitrile(9Ci)
CAS No.	485812-75-7
Molecular Formula	C8H12N2O
Molecular Weight	152.20 g/mol
Synonyms	8-Oxa-3-azabicyclo[3.2.1]octane-3-acetonitrile; 3-Azabicyclo[3.2.1]octane-3-acetonitrile, 8-oxa-; 485812-75-7; 8-Oxa-3-azabicyclo[3.2.1]octane-3-acetonitrile (9CI); Bicyclo[3.2.1]octane-3-acetonitrile, 8-oxa-3-aza-; 3-(Cyanomethyl)-8-oxa-3-azabicyclo[3.2.1]octane
EINECS	Contact for details

Quality Control

Our 8-Oxa-3-Azabicyclo[3.2.1]Octane-3-Acetonitrile(9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications in cGMP environments and advanced research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.