Description

Potassium (2-Trimethylsilyl)Ethynyltrifluoroborate is a versatile and highly valuable organoboron reagent used in modern synthetic chemistry. Its primary value lies in its role as a stable, shelf-stable source of the (2-trimethylsilyl)ethynyl anion, enabling efficient carbon-carbon bond formation under mild conditions. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries, facilitating the synthesis of complex molecules, functionalized alkynes, and novel polymers.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for introducing the (2-trimethylsilyl)ethynyl group into aromatic and heteroaromatic systems to create advanced intermediates.
• Pharmaceutical Intermediate Synthesis: Used in the construction of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing alkyne functionalities.
• Agrochemical Development: Employed in the synthesis of novel herbicides, fungicides, and insecticides that require specific alkyne-based architectures.
• Material Science & Polymer Chemistry: Serves as a monomer or building block for creating conductive polymers, organic semiconductors, and other functional materials.
• Ligand & Catalyst Development: Used to synthesize novel phosphine or N-heterocyclic carbene (NHC) ligands with alkyne handles for metal coordination.
• Chemical Biology & Bioconjugation: Facilitates the site-specific labeling of proteins, peptides, and other biomolecules via click chemistry or other bioorthogonal reactions.
• Organic Synthesis Research: A fundamental tool in academic and industrial R&D for exploring new synthetic methodologies and constructing complex natural product analogs.

Basic Information

Product Name	Potassium (2-Trimethylsilyl)Ethynyltrifluoroborate
CAS No.	485339-09-1
Molecular Formula	C7H13BF3KSi
Molecular Weight	232.17 g/mol
Synonyms	Potassium (2-Trimethylsilyl)ethynyltrifluoroborate; Potassium (Trimethylsilyl)ethynyltrifluoroborate; Potassium (2-Trimethylsilylethynyl)trifluoroborate; (2-Trimethylsilylethynyl)trifluoroborate Potassium Salt; Potassium (Trimethylsilylethynyl)trifluoroborate; TMS-Ethynyl-BF3K; Potassium (Trimethylsilyl)ethynyl-trifluoroborate; Potassium (TMS-ethynyl)trifluoroborate
EINECS	Contact for details

Quality Control

Our Potassium (2-Trimethylsilyl)Ethynyltrifluoroborate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for demanding synthetic applications. Each lot is analyzed using advanced techniques including NMR (1H, 13C, 11B, 19F) and HPLC to verify identity, purity, and the absence of critical impurities. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. This material is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (argon or nitrogen) to prevent decomposition. For long-term storage, maintain at 2-8°C. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Assay (NMR)	≥ 97%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.