Description

Potassium 4-(tert-Butyldimethylsilyloxy)But-1-Ynyltrifluoroborate is a highly versatile organoboron reagent, specifically a potassium organotrifluoroborate salt, prized for its stability and reactivity in advanced synthetic transformations. This compound is engineered to provide a protected, yet reactive, alkyne handle for precise carbon-carbon bond formation, offering superior shelf-life and handling compared to traditional boronic acids. It is an essential building block for researchers and process chemists in pharmaceutical development, agrochemical synthesis, and materials science, enabling the construction of complex molecular architectures.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: Acts as a stable, air- and moisture-tolerant coupling partner for the synthesis of biaryl and alkynyl-substituted compounds.
• Pharmaceutical Intermediate Synthesis: Key building block in the production of active pharmaceutical ingredients (APIs) and complex drug candidates, particularly those requiring alkynyl motifs.
• Agrochemical Research & Development: Used in the synthesis of novel herbicides, fungicides, and plant growth regulators.
• Material Science & Polymer Chemistry: Employed in the creation of conjugated polymers, organic electronic materials, and advanced functional materials.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands and organometallic catalysts.
• Chemical Biology & Probe Synthesis: Useful for incorporating alkynyl tags into biomolecules for labeling, imaging, and proteomics studies via click chemistry.

Basic Information

Product Name	Potassium 4-(tert-Butyldimethylsilyloxy)But-1-Ynyltrifluoroborate
CAS No.	485339-05-7
Molecular Formula	C10H19BF3KOSi
Molecular Weight	290.26 g/mol
Synonyms	Potassium (4-((tert-Butyldimethylsilyl)oxy)but-1-yn-1-yl)trifluoroborate; Potassium (4-(tert-Butyldimethylsiloxy)-1-butynyl)trifluoroborate; 4-(tert-Butyldimethylsilyloxy)-1-butynyltrifluoroborate Potassium Salt; TBDMS-Protected Potassium Alkyne Trifluoroborate; Potassium 4-((tert-Butyldimethylsilyl)oxy)but-1-yn-1-yltrifluoroborate
EINECS	Contact for details

Quality Control

Our Potassium 4-(tert-Butyldimethylsilyloxy)But-1-Ynyltrifluoroborate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including NMR (1H, 13C, 11B, 19F) and HPLC analysis, to ensure high chemical purity and consistent performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (argon or nitrogen) to maintain stability and prevent decomposition. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95%
Water Content (KF)	≤1.0%
NMR Assay (1H/19F)	≥90%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.