Description

3-Methoxycyclobutanecarboxylic Acid is a versatile and high-value cyclobutane derivative, serving as a critical chiral building block in advanced organic synthesis. Its unique strained ring structure functionalized with a carboxylic acid and methoxy group makes it an essential intermediate for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in programs targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the design and production of novel herbicides, fungicides, and insecticides, leveraging its rigid cyclobutane core for enhanced biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis to achieve high enantioselectivity.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced organic materials where the cyclobutane ring imparts specific thermal or mechanical properties.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes and tools to study enzyme function and biological pathways.

Basic Information

Product Name	3-Methoxycyclobutanecarboxylic Acid
CAS No.	480450-03-1
Molecular Formula	C7H12O3
Molecular Weight	144.17 g/mol
Synonyms	3-Methoxycyclobutane-1-carboxylic Acid; Cyclobutanecarboxylic acid, 3-methoxy-; 1-Carboxy-3-methoxycyclobutane; 3-Methoxy-1-cyclobutanecarboxylic Acid; (3-Methoxycyclobutyl)carboxylic Acid
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for all our fine chemical intermediates. Production of 3-Methoxycyclobutanecarboxylic Acid adheres to current Good Manufacturing Practices (cGMP) where applicable, ensuring batch-to-batch consistency and reliability. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. Our quality systems are designed to meet the exacting standards of pharmaceutical and R&D customers globally.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents, strong bases, and heat sources.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.