Description

1-Methyl-1H-Pyrazole-5-Sulfonyl Chloride is a versatile and highly reactive sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its ability to act as a sulfonylation reagent, facilitating the introduction of the sulfonyl functional group into target molecules with high efficiency. This compound is essential for research chemists and process development scientists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of sulfonamide-based drugs.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that incorporate sulfonyl moieties.
• Material Science Research: Employed in the creation of specialty polymers, dyes, and functional materials that require sulfonated structures.
• Chemical Biology & Proteomics: Acts as a reagent for modifying peptides, proteins, and other biomolecules via sulfonylation reactions in probe development.
• Custom Synthesis & Contract Manufacturing: A fundamental reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	1-Methyl-1H-Pyrazole-5-Sulfonyl Chloride
CAS No.	479552-18-6
Molecular Formula	C4H5ClN2O2S
Molecular Weight	180.61 g/mol
Synonyms	1-Methyl-1H-pyrazole-5-sulfonyl chloride; 1-Methylpyrazole-5-sulfonyl chloride; 5-(Chlorosulfonyl)-1-methyl-1H-pyrazole; 1-Methyl-5-sulfonylchloride pyrazole; 1-Methylpyrazol-5-ylsulfonyl chloride; Pyrazole-5-sulfonyl chloride, 1-methyl-; 1-Methyl-1H-pyrazol-5-sulfonyl chloride
EINECS	Contact for details

Quality Control

Our 1-Methyl-1H-Pyrazole-5-Sulfonyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, suitable for demanding synthetic applications. We provide comprehensive analytical documentation, including Certificates of Analysis (COA) with detailed HPLC/GC purity data and impurity profiles. Our quality system is designed to meet the stringent requirements of research and development as well as scale-up processes in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.