Description

(R)-3-(p-Methylphenyl)-β-Alanine is a high-purity chiral β-amino acid derivative, specifically the (R)-enantiomer. This compound is a critical chiral building block and intermediate in the synthesis of advanced pharmaceutical active ingredients and fine chemicals. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for applications requiring high stereochemical purity.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of novel Active Pharmaceutical Ingredients (APIs), particularly in therapeutic areas targeting the central nervous system and metabolic diseases.
• Peptide Synthesis: Used as a non-natural amino acid analog in the synthesis of constrained peptides and peptidomimetics to modulate biological activity and stability.
• Agrochemical Research: Serves as a precursor in the development of chiral herbicides, fungicides, and plant growth regulators with enhanced efficacy and selectivity.
• Ligand and Catalyst Development: Employed in the design and synthesis of chiral ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Bioconjugation and Probe Synthesis: Useful for creating labeled compounds and molecular probes for biochemical and diagnostic research.
• Fine Chemical Synthesis: A versatile building block for synthesizing complex organic molecules with specific stereochemical configurations in custom synthesis projects.

Basic Information

Product Name	(R)-3-(p-Methylphenyl)-β-Alanine
CAS No.	479064-87-4
Molecular Formula	C10H13NO2
Molecular Weight	179.22 g/mol
Synonyms	(R)-3-(4-Methylphenyl)-β-alanine; (R)-3-(4-Methylphenyl)-3-aminopropanoic acid; (R)-3-Amino-3-(4-methylphenyl)propanoic acid; D-3-(p-Tolyl)-β-alanine; (R)-3-(p-Tolyl)alanine; (R)-3-(4-Methylphenyl)-β-aminopropionic acid; (R)-Homo-4-methylphenylalanine
EINECS	Contact for details

Quality Control

Our (R)-3-(p-Methylphenyl)-β-Alanine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, confirming identity, purity, and enantiomeric excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.