Description

Hexamethylguanidinium Perfluoroisopropanolate is a highly specialized, non-nucleophilic superbase salt, valued for its exceptional deprotonation power in demanding chemical environments. Its primary commercial significance lies in facilitating challenging organic transformations, particularly in the synthesis of advanced materials and active pharmaceutical ingredients (APIs) where traditional bases fail. This compound is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty polymer industries seeking to optimize reaction yields and enable novel synthetic pathways.

Application

• Pharmaceutical Synthesis: As a potent, non-nucleophilic base for deprotonation and condensation reactions in the manufacture of complex drug molecules and intermediates.
• Advanced Polymerization Catalyst: Employed as an initiator or co-catalyst in the production of high-performance fluoropolymers and other specialty plastics.
• Agrochemical Intermediate Production: Used in the synthesis of key precursors for modern pesticides and herbicides requiring fluorinated components.
• Organic Light-Emitting Diode (OLED) Materials: Facilitates the synthesis of electron-transport and emissive layer materials in display technology.
• Lithium-Ion Battery Electrolyte Additive: Investigated for use in formulating advanced electrolytes to improve battery stability and performance.
• Academic & Industrial R&D: A critical reagent for methodological development in organic chemistry and process chemistry research.

Basic Information

Product Name	Hexamethylguanidinium Perfluoroisopropanolate
CAS No.	479024-69-6
Molecular Formula	C10H19F6N3O
Molecular Weight	311.27 g/mol
Synonyms	Hexamethylguanidine Hexafluoroisopropanol Salt; HMG-PFIP; 1,1,1,3,3,3-Hexamethylguanidinium 1,1,1,3,3,3-Hexafluoro-2-propanolate; Perfluoro-tert-butoxide Base Salt; Superbase Salt HMGN+(OCH(CF3)2)-; Non-nucleophilic Superbase Reagent; Guanidinium Fluorinated Alkoxide
EINECS	Contact for details

Quality Control

Our Hexamethylguanidinium Perfluoroisopropanolate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including NMR, HPLC, and Karl Fischer titration, to ensure high purity and consistent performance. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (argon or nitrogen) after opening to prevent decomposition. Keep away from incompatible materials such as strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5% w/w
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.