Description

N,N,N',N'-Tetramethyl-N'',N''-Diethylguanidinium Trimethyldifluorosilikonate is a highly reactive, specialized organosilicon salt that serves as a powerful fluoride source and superbase. This compound matters for its dual functionality, enabling critical reactions in advanced material synthesis where precise control over both basicity and fluorination is required. It is primarily needed by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty polymer industries for applications such as catalyst development and the synthesis of silicon-containing bioactive molecules.

Application

• As a powerful, non-nucleophilic superbase for deprotonation reactions in sensitive organic syntheses.
• As a fluoride ion source for desilylation and silicon-fluorine bond formation in organosilicon chemistry.
• Key reagent in the synthesis of silicon-based pharmaceuticals and agrochemical intermediates.
• Catalyst or co-catalyst component in polymerization reactions for producing specialty silicones and fluoropolymers.
• Used in surface modification and functionalization of silica and other inorganic materials.
• Employed in electrolyte formulations for advanced battery research.
• Facilitates cross-coupling reactions in medicinal chemistry where strong, hindered bases are advantageous.

Basic Information

Product Name	N,N,N',N'-Tetramethyl-N'',N''-Diethylguanidinium Trimethyldifluorosilikonate
CAS No.	479024-65-2
Molecular Formula	C₁₂H₃₀F₂N₄Si
Molecular Weight	296.48 g/mol
Synonyms	Tetramethyldiethylguanidinium Trimethyldifluorosilicate; TMTEG·TMSiF₂; N,N,N',N'-Tetramethyl-N'',N''-diethylguanidinium difluorotrimethylsilicate; Guanidinium, N,N,N',N'-tetramethyl-N'',N''-diethyl-, salt with difluorotrimethylsilane (1:1); Difluorotrimethylsiliconic acid tetramethyldiethylguanidinium salt; Superbase Fluoride Reagent; TMSiF₂-TMEDG Salt
EINECS	Contact for details

Quality Control

Our N,N,N',N'-Tetramethyl-N'',N''-Diethylguanidinium Trimethyldifluorosilikonate is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including NMR and HPLC, to ensure high chemical purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Due to its hygroscopic and fluoride/strong alkali nature, this material must be stored under a dry, inert atmosphere (e.g., argon or nitrogen) in a cool, dry place (15-25°C). Ensure the storage area is well-ventilated and separate from acids and moisture-sensitive compounds.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.