Description

Ethanone, 1-[(1R,3R,4S)-3-Hydroxybicyclo[2.2.1]Hept-2-Yl]-, Rel- (9Ci) is a high-purity, stereochemically defined chiral building block. This compound is valued for its rigid bicyclic framework and functional handles, making it a critical intermediate in advanced organic synthesis. It is primarily sought by research and development teams in the pharmaceutical and fine chemical industries for the synthesis of novel active pharmaceutical ingredients (APIs) and complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new therapeutic agents, particularly for central nervous system (CNS) and antiviral drugs.
• Asymmetric Synthesis: Used as a building block in catalytic asymmetric reactions to construct complex molecules with high enantiomeric purity.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization due to its defined three-dimensional structure.
• Fine Chemical Production: Acts as a precursor for the manufacture of specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Academic & Industrial R&D: Utilized in methodological development and the synthesis of novel organic compounds for material science and chemical biology.

Basic Information

Product Name	Ethanone, 1-[(1R,3R,4S)-3-Hydroxybicyclo[2.2.1]Hept-2-Yl]-, Rel- (9Ci)
CAS No.	478943-97-4
Molecular Formula	C9H14O2
Molecular Weight	154.21 g/mol
Synonyms	rel-(1R,3R,4S)-3-Hydroxybicyclo[2.2.1]heptan-2-yl methyl ketone; 1-[(1R,3R,4S)-3-Hydroxybicyclo[2.2.1]hept-2-yl]ethanone; (1R,3R,4S)-3-Acetyl-2-norbornanol; Bicyclo[2.2.1]heptan-2-ol, 3-acetyl-, (1R,3R,4S)-rel-; 3-Acetyl-2-norbornanol (rel-(1R,3R,4S)-); Chiral norbornane ketone derivative
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. We employ advanced analytical techniques including HPLC, GC, and chiral analysis to guarantee high chemical and enantiomeric purity. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request. Production can adhere to cGMP guidelines for pharmaceutical applications as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.