Description

Ethanone, 1-[(1R,4S,6S)-6-Hydroxybicyclo[2.2.1]Hept-2-Yl]-, Rel- (9Ci) CAS NO 478943-94-1 is a high-purity, stereochemically defined bicyclic ketone derivative, serving as a critical chiral building block in advanced organic synthesis. Its unique rigid structure and functional groups make it an invaluable intermediate for constructing complex molecular architectures with precise spatial orientation. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of complex drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Research: Used in the development of novel, stereoselective pesticides and herbicides where the specific spatial configuration impacts biological activity.
• Asymmetric Catalysis: Employed as a ligand precursor or a chiral auxiliary in catalytic reactions to induce enantioselectivity.
• Material Science: Serves as a monomer or cross-linking agent for synthesizing specialty polymers with tailored thermal and mechanical properties.
• Flavor & Fragrance Chemistry: A potential intermediate for creating novel, complex odorants and flavoring agents with unique organoleptic profiles.
• Academic & Process Chemistry: Used in methodological studies and scale-up process development for stereocontrolled synthetic routes.

Basic Information

Item	Details
Product Name	Ethanone, 1-[(1R,4S,6S)-6-Hydroxybicyclo[2.2.1]Hept-2-Yl]-, Rel- (9Ci)
CAS No.	478943-94-1
Molecular Formula	C9H14O2
Molecular Weight	154.21 g/mol
Synonyms	rel-(1R,4S,6S)-6-Hydroxybicyclo[2.2.1]heptan-2-yl methyl ketone; (1R,4S,6S)-6-Hydroxy-2-norbornyl methyl ketone (rel); Bicyclo[2.2.1]heptan-2-one, 6-hydroxy-, methyl-, (1R,4S,6S)-rel-; 6-Hydroxy-2-norbornanemethyl ketone; Chiral Bicyclic Hydroxy Ketone; CAS 478943-94-1
EINECS	Contact for details

Quality Control

Every batch of Ethanone, 1-[(1R,4S,6S)-6-Hydroxybicyclo[2.2.1]Hept-2-Yl]-, Rel- (9Ci) is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, chiral chromatography, and NMR to ensure identity, purity, and stereochemical integrity. Certificates of Analysis (COA) detailing all critical parameters are provided with each shipment. Our quality commitment aligns with cGMP and ISO 9001 principles for traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.