Description

2H-Pyran-2-Carboxaldehyde, Tetrahydro-6-Methoxy-5-Methyl-, (2S,5S,6S)- (9Ci) is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. Its value lies in its complex, functionalized pyran ring structure, which serves as a versatile precursor for the development of pharmaceuticals and fine chemicals. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require precise molecular architecture for creating novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new therapeutic agents, particularly in antiviral, anticancer, and neurological drug candidates.
• Asymmetric Synthesis: Utilized as a sophisticated starting material or intermediate in stereoselective reactions to construct complex natural products and bioactive molecules.
• Agrochemical Research: Serves as a building block for novel pesticides, herbicides, or plant growth regulators requiring specific stereochemistry for optimal activity.
• Flavor & Fragrance Chemistry: Potential precursor for the synthesis of complex, naturally-derived odorants and flavoring agents with specific olfactory properties.
• Material Science Research: Investigated as a monomer or functional component in the development of advanced polymers with specialized optical or chemical properties.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) conducting cutting-edge research in synthetic methodology and medicinal chemistry.

Basic Information

Product Name	2H-Pyran-2-Carboxaldehyde, Tetrahydro-6-Methoxy-5-Methyl-, (2S,5S,6S)- (9Ci)
CAS No.	478693-75-3
Molecular Formula	C8H14O3
Molecular Weight	158.20 g/mol
Synonyms	(2S,5S,6S)-Tetrahydro-6-methoxy-5-methyl-2H-pyran-2-carboxaldehyde; (2S,5S,6S)-6-Methoxy-5-methyltetrahydro-2H-pyran-2-carbaldehyde; 5-Methyl-6-methoxytetrahydro-2H-pyran-2-carboxaldehyde (stereoisomer); Chiral Tetrahydro-2H-pyran-2-carboxaldehyde derivative; 2H-Pyran-2-carboxaldehyde, tetrahydro-6-methoxy-5-methyl-, (2S,5S,6S)-; 478693-75-3; (2S,5S,6S)-6-Methoxy-5-methyltetrahydropyran-2-carbaldehyde
EINECS	Contact for details

Quality Control

Every batch of our chiral intermediates is produced and tested under a strict quality management system. We provide comprehensive Certificates of Analysis (COA) that detail identity, purity, and stereochemical integrity, typically verified by techniques such as chiral HPLC, GC, NMR, and optical rotation. Our commitment ensures the material meets the exacting standards required for research and development applications. Custom purity grades and analytical packages are available to support specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place at 2-8°C for long-term stability. This compound is easily oxidized and light-sensitive; allow the sealed container to reach ambient temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Optical Rotation	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.