Description

2H-Pyran-2-Methanol,Tetrahydro-6-Methoxy-5-Methyl-,(2S,5S,6S)-(9Ci) is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. Its precise molecular architecture makes it a valuable intermediate for constructing complex molecules with specific three-dimensional orientations. This compound is primarily utilized by research institutions and pharmaceutical development teams working on novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals. The CAS number for this material is 478693-67-3.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, particularly for complex, stereospecific drug molecules.
• Agrochemical Synthesis: Used in the creation of advanced, enantiomerically pure pesticides and herbicides where specific biological activity is required.
• Asymmetric Catalysis Research: Serves as a precursor or ligand in the development of new catalytic systems for stereoselective chemical transformations.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals, flavors, and fragrances requiring high stereochemical fidelity.
• Academic & Industrial R&D: A valuable tool for chemists in universities and corporate labs exploring new synthetic methodologies and complex natural product synthesis.

Basic Information

Product Name	2H-Pyran-2-Methanol,Tetrahydro-6-Methoxy-5-Methyl-,(2S,5S,6S)-(9Ci)
CAS No.	478693-67-3
Molecular Formula	C8H16O3
Molecular Weight	160.21 g/mol
Synonyms	(2S,5S,6S)-6-Methoxy-5-methyltetrahydro-2H-pyran-2-methanol; (2S,5S,6S)-Tetrahydro-6-methoxy-5-methyl-2H-pyran-2-methanol; 2H-Pyran-2-methanol, tetrahydro-6-methoxy-5-methyl-, (2S,5S,6S)-; (2S,5S,6S)-5-Methyl-6-methoxytetrahydropyran-2-ylmethanol; A stereoisomer of Dihydromethyllipoic acid derivative; Chiral tetrahydropyran methanol.
EINECS	Contact for details

Quality Control

Our production of this chiral intermediate adheres to stringent quality control protocols to ensure batch-to-batch consistency and high chemical purity, typically exceeding 97% (by HPLC). Identity is confirmed via spectroscopic methods (NMR, IR, MS). Each batch is supplied with a comprehensive Certificate of Analysis (COA) detailing purity, chiral purity (enantiomeric excess), and impurity profile. We support development projects requiring compliance with cGMP guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% e.e.
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.