Description

1,4-Dibromo-2,5-Bis[2-(Trimethylsilyl)Ethynyl]Benzene is a high-value, multi-functional organic building block characterized by its brominated aromatic core and terminal trimethylsilyl-protected acetylene groups. This compound matters for its role as a versatile precursor in advanced material synthesis, enabling precise molecular architecture through cross-coupling and deprotection reactions. It is primarily needed by R&D chemists and process engineers in the pharmaceutical, agrochemical, and organic electronics industries for constructing complex molecules and functional polymers.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the synthesis of active pharmaceutical ingredients (APIs) and complex drug candidates via Sonogashira and Suzuki-Miyaura cross-coupling reactions.
• Organic Semiconductor Precursor: Used in the development of conjugated polymers and small molecules for organic light-emitting diodes (OLEDs), field-effect transistors (OFETs), and photovoltaic cells.
• Agrochemical Synthesis: Acts as a building block for creating novel herbicides, fungicides, and insecticides with tailored properties.
• Material Science Research: Employed in the construction of metal-organic frameworks (MOFs), covalent organic frameworks (COFs), and other porous materials for catalysis and gas storage.
• Ligand and Catalyst Development: Utilized to synthesize sophisticated phosphine or N-heterocyclic carbene (NHC) ligands for transition metal catalysis.
• Chemical Probe Synthesis: Fundamental for creating fluorescent tags, molecular sensors, and other diagnostic tools in biochemical research.

Basic Information

Product Name	1,4-Dibromo-2,5-Bis[2-(Trimethylsilyl)Ethynyl]Benzene
CAS No.	478190-79-3
Molecular Formula	C18H22Br2Si2
Molecular Weight	478.45 g/mol
Synonyms	1,4-Dibromo-2,5-bis(2-trimethylsilylethynyl)benzene; 2,5-Dibromo-1,4-bis(2-trimethylsilylethynyl)benzene; 1,4-Bis(2-trimethylsilylethynyl)-2,5-dibromobenzene; Benzene, 1,4-dibromo-2,5-bis[2-(trimethylsilyl)ethynyl]-; TMS-protected Dibromo-Diethynylbenzene; Dibromo-Bis(TMS-ethynyl)Benzene
EINECS	Contact for details

Quality Control

Our 1,4-Dibromo-2,5-Bis[2-(Trimethylsilyl)Ethynyl]Benzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.