Description

3-(4-[(4-Fluorophenyl)Sulfonyl]Piperazino)-6-Phenylpyridazine is a high-purity, non-nucleoside reverse transcriptase inhibitor (NNRTI) intermediate of significant interest in pharmaceutical research and development. This compound matters for its critical role in the synthesis of novel therapeutic agents targeting viral infections, offering a sophisticated chemical scaffold for drug discovery. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries, particularly those focused on antiviral and central nervous system (CNS) drug candidates.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of next-generation Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs) for antiviral therapies.
• Biochemical Research: Used as a reference standard and probe compound in enzymatic assays and virology studies.
• Drug Discovery & Development: Serves as a core scaffold for medicinal chemistry programs aimed at optimizing potency and pharmacokinetic properties.
• Process Chemistry: Employed in route scouting and scale-up studies for the commercial manufacturing of active pharmaceutical ingredients (APIs).
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and development services for the life sciences sector.

Basic Information

Product Name	3-(4-[(4-Fluorophenyl)Sulfonyl]Piperazino)-6-Phenylpyridazine
CAS No.	478077-49-5
Molecular Formula	C21H19FN4O2S
Molecular Weight	410.47 g/mol
Synonyms	3-[4-(4-Fluorophenyl)sulfonylpiperazin-1-yl]-6-phenylpyridazine; 6-Phenyl-3-[4-[(4-fluorophenyl)sulfonyl]-1-piperazinyl]pyridazine; 3-(4-(4-Fluorobenzenesulfonyl)piperazin-1-yl)-6-phenylpyridazine; BMS-561389; BMS 561389; BMS561389; NNRTI Intermediate 478077-49-5; 1-[6-Phenyl-3-pyridazinyl]-4-[(4-fluorophenyl)sulfonyl]piperazine
EINECS	Contact for details

Quality Control

Our 3-(4-[(4-Fluorophenyl)Sulfonyl]Piperazino)-6-Phenylpyridazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.