Description

6-Chloro-3-(difluoromethyl)[1,2,4]triazolo[4,3-b]pyridazine is a high-purity, heterocyclic organic compound with the CAS number 477889-88-6, serving as a critical advanced intermediate in modern synthetic chemistry. Its unique fused triazolopyridazine core, functionalized with chloro and difluoromethyl groups, makes it an exceptionally valuable building block for constructing complex molecular architectures. This compound is primarily sought after by R&D and process chemistry teams in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

This specialized intermediate is engineered for high-value synthesis applications, particularly where the introduction of a fluorinated heterocyclic scaffold is required.

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in kinase inhibitor and antiviral research.
• Agrochemical Active Ingredient Development: Used in the research and synthesis of new generation herbicides and fungicides, leveraging the biological activity of the triazolopyridazine moiety.
• Material Science Research: Serves as a precursor for developing specialty chemicals and functional materials with specific electronic or photophysical properties.
• Organic Synthesis & Process Chemistry: A versatile reagent for constructing complex nitrogen-containing heterocycles in academic and industrial research settings.

Basic Information

Product Name	6-Chloro-3-(difluoromethyl)[1,2,4]triazolo[4,3-b]pyridazine
CAS No.	477889-88-6
Molecular Formula	C7H3ClF2N4
Molecular Weight	216.57 g/mol
Synonyms	6-Chloro-3-(difluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazine; [1,2,4]Triazolo[4,3-b]pyridazine, 6-chloro-3-(difluoromethyl)-; 6-Chloro-3-difluoromethyl-[1,2,4]triazolo[4,3-b]pyridazine; 6-Chloro-3-(difluoromethyl)-1,2,4-triazolo[4,3-b]pyridazine; 477889-88-6; C7H3ClF2N4; AKOS025310626; FT-0775787
EINECS	Contact for details

Quality Control

Our production of 6-Chloro-3-(difluoromethyl)[1,2,4]triazolo[4,3-b]pyridazine adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR, and MS, to confirm identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is sensitive to strong alkalis and fluorides; keep away from incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.