Description

6-Phenyl-5-[4-(Phenylsulfonyl)Piperazino]-3(2H)-Pyridazinone is a high-purity, advanced pharmaceutical intermediate characterized by its unique pyridazinone core functionalized with a phenylsulfonyl piperazine moiety. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel drug candidates with targeted biological activity. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within central nervous system (CNS) and anti-inflammatory research pipelines.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new chemical entities (NCEs) for potential drug applications.
• Medicinal Chemistry Research: Used as a core scaffold or precursor for constructing libraries of compounds in structure-activity relationship (SAR) studies.
• CNS Drug Discovery: Serves as a valuable intermediate in the synthesis of compounds targeting neurological pathways and receptors.
• Enzyme Inhibitor Development: Potential building block for molecules designed to modulate specific enzymatic activity.
• Preclinical & Process Chemistry: Employed in scale-up studies and route optimization for potential Active Pharmaceutical Ingredient (API) synthesis.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and development services for the life sciences sector.

Basic Information

Product Name	6-Phenyl-5-[4-(Phenylsulfonyl)Piperazino]-3(2H)-Pyridazinone
CAS No.	477872-20-1
Molecular Formula	C20H20N4O3S
Molecular Weight	396.46 g/mol
Synonyms	5-[4-(Phenylsulfonyl)piperazin-1-yl]-6-phenyl-2,3-dihydropyridazin-3-one; 6-Phenyl-5-(4-phenylsulfonylpiperazin-1-yl)pyridazin-3(2H)-one; 477872-20-1; 5-(4-Benzenesulfonylpiperazin-1-yl)-6-phenyl-1,2-dihydropyridazin-3-one; 6-Phenyl-5-(4-(phenylsulfonyl)piperazin-1-yl)-2,3-dihydropyridazin-3-one
EINECS	Contact for details

Quality Control

Our 6-Phenyl-5-[4-(Phenylsulfonyl)Piperazino]-3(2H)-Pyridazinone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee traceability, consistency, and compliance with your research protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.