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4-Chloro-5-[4-(3-Chlorophenyl)Piperazino]-2-(4-Methoxyphenyl)-3(2H)-Pyridazinone CAS NO 477867-46-2


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CAS No.:477867-46-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

4-Chloro-5-[4-(3-Chlorophenyl)Piperazino]-2-(4-Methoxyphenyl)-3(2H)-Pyridazinone is a high-purity, synthetically derived pyridazinone derivative that serves as a critical advanced intermediate in modern pharmaceutical research and development. Its complex heterocyclic structure, featuring both chlorophenyl and methoxyphenyl substituents, makes it a valuable scaffold for the synthesis of novel bioactive compounds. This product is essential for medicinal chemists and R&D departments in the pharmaceutical and agrochemical industries focused on developing new therapeutic agents or crop protection solutions.

Application

  • Pharmaceutical Intermediate: A key building block for the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, cardiovascular diseases, or other therapeutic areas.
  • Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to develop novel small-molecule therapeutics.
  • Agrochemical R&D: Serves as a precursor in the development of new herbicides, fungicides, or insecticides, leveraging its heterocyclic core.
  • Biochemical Tool Compound: Potential use as a research-grade ligand or inhibitor in biochemical assays to study specific enzyme or receptor pathways.
  • Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client projects.
  • Academic Research: Utilized in university and institutional laboratories for fundamental studies in organic synthesis and heterocyclic chemistry.

Basic Information

Item Details
Product Name 4-Chloro-5-[4-(3-Chlorophenyl)Piperazino]-2-(4-Methoxyphenyl)-3(2H)-Pyridazinone
CAS No. 477867-46-2
Molecular Formula C21H20Cl2N4O2
Molecular Weight 431.32 g/mol
Synonyms 4-Chloro-5-[4-(3-chlorophenyl)-1-piperazinyl]-2-(4-methoxyphenyl)-2,3-dihydropyridazin-3-one; 5-[4-(3-Chlorophenyl)piperazin-1-yl]-4-chloro-2-(4-methoxyphenyl)pyridazin-3(2H)-one; 4-Chloro-5-(4-(3-chlorophenyl)piperazin-1-yl)-2-(4-methoxyphenyl)-2H-pyridazin-3-one; CAS 477867-46-2; Pyridazinone derivative intermediate; 3(2H)-Pyridazinone, 4-chloro-5-[4-(3-chlorophenyl)-1-piperazinyl]-2-(4-methoxyphenyl)-
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Quality Control

Every batch of 4-Chloro-5-[4-(3-Chlorophenyl)Piperazino]-2-(4-Methoxyphenyl)-3(2H)-Pyridazinone is manufactured under a strict quality management system and undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Our products are characterized using advanced techniques including HPLC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing all relevant specifications are provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 20 ppm
Single Unknown Impurity (HPLC) ≤ 0.5%
Total Impurities (HPLC) ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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