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4-Chloro-2-(4-Methoxyphenyl)-5-([2-(2-Pyridinyl)Ethyl]Amino)-3(2H)-Pyridazinone CAS NO 477867-44-0


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CAS No.:477867-44-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

4-Chloro-2-(4-Methoxyphenyl)-5-([2-(2-Pyridinyl)Ethyl]Amino)-3(2H)-Pyridazinone is a high-purity, synthetically derived pyridazinone derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical pharmacological intermediate and a versatile scaffold for medicinal chemists exploring novel therapeutic agents. It is primarily needed by R&D laboratories, contract research organizations (CROs), and pharmaceutical companies focused on drug discovery programs targeting central nervous system (CNS) disorders, inflammation, and other complex disease pathways.

Application

  • Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting neurological and inflammatory pathways.
  • Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery projects.
  • Biochemical Tool Compound: Employed in in vitro assays to study enzyme inhibition or receptor modulation for target validation.
  • Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis and scale-up projects.
  • Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis and pharmacology.
  • Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name 4-Chloro-2-(4-Methoxyphenyl)-5-([2-(2-Pyridinyl)Ethyl]Amino)-3(2H)-Pyridazinone
CAS No. 477867-44-0
Molecular Formula C18H17ClN4O2
Molecular Weight 356.81 g/mol
Synonyms 4-Chloro-2-(4-methoxyphenyl)-5-[(2-pyridin-2-ylethyl)amino]pyridazin-3(2H)-one; 5-[(2-Pyridin-2-ylethyl)amino]-4-chloro-2-(4-methoxyphenyl)-2,3-dihydropyridazin-3-one; CAS 477867-44-0; 4-Chloro-2-(p-methoxyphenyl)-5-[(2-(2-pyridyl)ethyl)amino]-3(2H)-pyridazinone; Pyridazinone derivative 477867-44-0; 5-((2-(Pyridin-2-yl)ethyl)amino)-4-chloro-2-(4-methoxyphenyl)pyridazin-3(2H)-one
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Quality Control

Our 4-Chloro-2-(4-Methoxyphenyl)-5-([2-(2-Pyridinyl)Ethyl]Amino)-3(2H)-Pyridazinone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with the standards expected for pharmaceutical R&D and advanced chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive; prolonged exposure to light should be avoided. Keep the container tightly sealed to protect from moisture.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (HPLC) Conforms to reference standard
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Water Content (KF) ≤ 0.5%
Residue on Ignition ≤ 0.1%
Heavy Metals ≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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