Description

2,2-Dimethyl-5-(([3-(Trifluoromethyl)Phenyl]Sulfanyl)Methylene)-1,3-Dioxane-4,6-Dione is a high-purity, specialized organic building block featuring a unique dioxanedione core functionalized with a trifluoromethylphenylthio moiety. This compound is valued for its role as a versatile synthon in advanced pharmaceutical and agrochemical research, enabling the introduction of complex molecular architectures. It is primarily sought by R&D chemists and process development scientists in the fine chemical and life science industries for synthesizing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Research: Used in the development of new-generation herbicides and fungicides, leveraging the biological activity of the trifluoromethyl and dioxanedione groups.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the development of specialty polymers with tailored thermal and chemical resistance properties.
• Organic Synthesis Reagent: Employed in cycloaddition reactions and as a Michael acceptor in complex molecule construction for academic and industrial research.
• Fluorinated Compound Library Synthesis: Essential for creating diverse screening libraries in medicinal chemistry, capitalizing on the metabolic stability imparted by the fluorine atoms.

Basic Information

Product Name	2,2-Dimethyl-5-(([3-(Trifluoromethyl)Phenyl]Sulfanyl)Methylene)-1,3-Dioxane-4,6-Dione
CAS No.	477866-39-0
Molecular Formula	C14H11F3O4S
Molecular Weight	332.30 g/mol
Synonyms	5-[(3-Trifluoromethylphenyl)thio]methylene-2,2-dimethyl-1,3-dioxane-4,6-dione; 2,2-Dimethyl-5-[(3-trifluoromethylphenyl)thio]methylene-1,3-dioxane-4,6-dione; Meldrum's acid derivative, 5-((3-(Trifluoromethyl)phenyl)thio)methylene-2,2-dimethyl-1,3-dioxane-4,6-dione; 477866-39-0; ATB-352; CAS 477866-39-0
EINECS	Contact for details

Quality Control

Our production of 2,2-Dimethyl-5-(([3-(Trifluoromethyl)Phenyl]Sulfanyl)Methylene)-1,3-Dioxane-4,6-Dione adheres to strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure consistency and compliance with research-grade specifications. Certificates of Analysis (COA) detailing batch-specific results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be sensitive to prolonged exposure to moisture and should be handled under an inert atmosphere for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.