Description

Carbamic Acid, (Tetrahydro-3-Oxo-2H-Pyran-4-Yl)-, 1,1-Dimethylethyl Ester (9Ci) is a specialized organic compound featuring a carbamate group linked to a tetrahydro-2H-pyran-4-one moiety, serving as a key synthetic intermediate. Its value lies in its role as a versatile building block for constructing complex molecular architectures, particularly in pharmaceutical research and development. This high-purity intermediate is essential for medicinal chemists and process development scientists in the life sciences industry who require reliable, high-quality raw materials for API synthesis and novel drug discovery programs.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting neurological and metabolic disorders.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Process Chemistry Development: Serves as a starting material or advanced intermediate in scaling up synthetic routes from laboratory to pilot plant and commercial production.
• Protease Inhibitor Synthesis: A potential precursor in the development of enzyme inhibitors, leveraging its carbamate and lactone-like structural features.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke molecules for clinical trials.
• Academic & Institutional Research: Utilized in university and institutional labs for fundamental organic synthesis projects and methodological development.

Basic Information

Product Name	Carbamic Acid, (Tetrahydro-3-Oxo-2H-Pyran-4-Yl)-, 1,1-Dimethylethyl Ester (9Ci)
CAS No.	477584-42-2
Molecular Formula	C10H17NO4
Molecular Weight	215.25 g/mol
Synonyms	tert-Butyl (tetrahydro-3-oxo-2H-pyran-4-yl)carbamate; 4-[[(1,1-Dimethylethoxy)carbonyl]amino]tetrahydro-2H-pyran-3-one; 4-(Boc-amino)dihydro-2H-pyran-3(4H)-one; (Tetrahydro-3-oxo-2H-pyran-4-yl)carbamic acid tert-butyl ester; Boc-4-aminotetrahydro-2H-pyran-3-one; 4-N-Boc-amino-3-oxotetrahydropyran
EINECS	Contact for details

Quality Control

Our Carbamic Acid, (Tetrahydro-3-Oxo-2H-Pyran-4-Yl)-, 1,1-Dimethylethyl Ester (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent batch-to-batch quality suitable for sensitive pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound is light-sensitive (store away from light). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.