Description

(4S,5R,6R)-5-Acetamido-4-Amino-6-((1R,2R)-2,3-Dihydroxy-1-Methoxypropyl)-5,6-Dihydro-4H-Pyran-2-Carboxylic Acid is a high-purity, stereochemically defined advanced pharmaceutical intermediate. This compound is critical for the synthesis of complex bioactive molecules, particularly in the development of novel antiviral and antibacterial agents. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in process chemistry and the production of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of neuraminidase inhibitors and other antiviral drugs.
• Antiviral Drug Research: Used in the R&D of next-generation influenza treatments and other viral infection therapies.
• Process Chemistry: Serves as a chiral precursor in multi-step synthetic routes for complex organic molecules.
• API Manufacturing: Employed in the commercial-scale production of specific active pharmaceutical ingredients requiring this precise stereochemistry.
• Biochemical Research: Utilized in studies of enzyme inhibition and carbohydrate-mimetic interactions.
• Reference Standard: Acts as a high-purity analytical standard for quality control in pharmaceutical production.

Basic Information

Product Name	(4S,5R,6R)-5-Acetamido-4-Amino-6-((1R,2R)-2,3-Dihydroxy-1-Methoxypropyl)-5,6-Dihydro-4H-Pyran-2-Carboxylic Acid
CAS No.	475483-21-7
Molecular Formula	C12H20N2O7
Molecular Weight	304.30 g/mol
Synonyms	5-Acetamido-4-amino-2,3,4,5-tetradeoxy-D-glycero-D-galacto-non-2-enopyranosonic acid; Relenza intermediate; Zanamivir intermediate; (1R,2R,3S,4R,5S)-4-Acetamido-5-amino-3-((1R,2R)-2,3-dihydroxy-1-methoxypropyl)-2,3,4,5-tetrahydroxycyclopent-1-enecarboxylic acid (tautomeric form); 4-Acetamido-5-amino-3-(1,2,3-trihydroxypropyl)-2,3,4,5-tetrahydroxycyclopent-1-enecarboxylic acid derivative; Peramivir related compound; Anti-influenza agent intermediate.
EINECS	Contact for details

Quality Control

Our (4S,5R,6R)-5-Acetamido-4-Amino-6-((1R,2R)-2,3-Dihydroxy-1-Methoxypropyl)-5,6-Dihydro-4H-Pyran-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high stereochemical purity and chemical identity. Certificates of Analysis (COA) detailing purity, impurities, and specific tests are provided to support cGMP and ICH Q7 compliant applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% de
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.