Description

2-Hydroxy-3,3-Dimethylbicyclo[2.2.1]heptane-1-carboxylic acid is a high-purity, functionalized bicyclic carboxylic acid derivative valued for its unique sterically hindered structure. This compound serves as a versatile and critical chiral building block in advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily sought after by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in areas requiring rigid, three-dimensional molecular scaffolds.
• Agrochemical Synthesis: Used in the design and synthesis of novel herbicides, fungicides, and plant growth regulators where its bicyclic structure can impart specific biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for creating sophisticated chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, including flavors, fragrances, and advanced materials.
• Academic and Industrial Research: A valuable tool for methodological studies in organic chemistry and for probing structure-activity relationships (SAR).

Basic Information

Product Name	2-Hydroxy-3,3-Dimethylbicyclo[2.2.1]heptane-1-Carboxylic Acid
CAS No.	474370-59-7
Molecular Formula	C10H16O3
Molecular Weight	184.23 g/mol
Synonyms	1-Norbornanecarboxylic acid, 2-hydroxy-3,3-dimethyl-; 3,3-Dimethyl-2-hydroxybicyclo[2.2.1]heptane-1-carboxylic acid; 2-Hydroxy-3,3-dimethylnorbornane-1-carboxylic acid; Dimethylhydroxynorbornanecarboxylic acid
EINECS	Contact for details

Quality Control

Our 2-Hydroxy-3,3-Dimethylbicyclo[2.2.1]heptane-1-carboxylic acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the stringent requirements of research and industrial synthesis. A detailed Certificate of Analysis (COA) providing full specifications and test results is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.