Description

(R)-1-(5-Methylfuran-2-Yl)Propan-1-Amine is a chiral amine building block of significant interest in advanced organic synthesis. Its value lies in its role as a key intermediate for constructing complex, optically active molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and process chemists developing active pharmaceutical ingredients (APIs), chiral catalysts, and fine chemicals where stereochemical control is paramount. The CAS number for this material is 473732-94-4.

Application

This chiral amine serves as a versatile intermediate in several high-value chemical synthesis pathways.

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel, stereospecific active pharmaceutical ingredients (APIs), including potential central nervous system (CNS) agents and antiviral compounds.
• Agrochemical Synthesis: Used in the research and development of chiral pesticides and herbicides, where the specific (R)-enantiomer can provide enhanced biological activity and environmental profile.
• Chiral Ligand & Catalyst Development: Employed as a precursor for synthesizing novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical & Specialty Chemical Production: Integral to the manufacture of complex fragrance molecules, flavors, and other high-purity specialty chemicals requiring defined stereochemistry.
• Academic & Industrial Research: A valuable reagent for methodological development in organic chemistry and for exploring new reaction pathways in process chemistry.

Basic Information

Product Name	(R)-1-(5-Methylfuran-2-Yl)Propan-1-Amine
CAS No.	473732-94-4
Molecular Formula	C8H13NO
Molecular Weight	139.20 g/mol
Synonyms	(R)-1-(5-Methyl-2-furyl)-1-propanamine; (R)-1-(5-Methylfuran-2-yl)propan-1-amine; (R)-α-Methyl-5-methyl-2-furanmethanamine; (R)-5-Methyl-2-furanpropanamine; (R)-1-(5-Methyl-2-furanyl)-1-propanamine; (R)-1-(5-Methylfuran-2-yl)propylamine; (R)-enantiomer of 1-(5-Methylfuran-2-yl)propan-1-amine
EINECS	Contact for details

Quality Control

Our (R)-1-(5-Methylfuran-2-Yl)Propan-1-Amine is produced under strict quality management protocols. We offer material suitable for research and development as well as scalable GMP-grade batches for pharmaceutical applications. All batches undergo comprehensive analytical testing including chiral purity determination (HPLC), identity confirmation (IR, NMR), and impurity profiling. Certificates of Analysis (COA) detailing exact specifications, including enantiomeric excess (ee), are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or when opening the container to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.