Description

4-(3-Methoxyphenyl)Tetrahydro-2H-Pyran-4-Carboxylic Acid is a high-value, synthetically versatile organic building block characterized by its tetrahydro-2H-pyran (oxane) ring substituted with a carboxylic acid and a 3-methoxyphenyl group. This compound matters for its role as a key chiral intermediate in the synthesis of complex molecules, offering a rigid scaffold for pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for constructing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral synthon in the research and development of new therapeutic agents, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Used in the design and production of novel herbicides, fungicides, and insecticides, leveraging its aromatic and heterocyclic structure.
• Ligand and Catalyst Development: Acts as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of monomers for specialty polymers or liquid crystals due to its rigid, functionalized core.
• Chemical Biology Probes: Utilized as a building block for developing molecular probes and inhibitors to study enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for fine chemical manufacturers offering bespoke synthesis services to the life sciences industry.

Basic Information

Product Name	4-(3-Methoxyphenyl)Tetrahydro-2H-Pyran-4-Carboxylic Acid
CAS No.	473706-26-2
Molecular Formula	C13H16O4
Molecular Weight	236.26 g/mol
Synonyms	4-(3-Methoxyphenyl)oxane-4-carboxylic acid; 4-(3-Methoxyphenyl)tetrahydropyran-4-carboxylic acid; 4-(m-Methoxyphenyl)tetrahydro-2H-pyran-4-carboxylic acid; 4-(3-Methoxyphenyl)-4-carboxytetrahydropyran; 4-Carboxy-4-(3-methoxyphenyl)tetrahydropyran; 473706-26-2; 4-(3-Methoxyphenyl)tetrahydro-2H-pyran-4-carboxylic acid CAS 473706-26-2
EINECS	Contact for details

Quality Control

Our 4-(3-Methoxyphenyl)Tetrahydro-2H-Pyran-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.