Description

4-(3-Chlorophenyl)-Tetrahydro-2H-Pyran-4-Carbonitrile is a versatile and high-value synthetic intermediate in organic chemistry. This compound is crucial for research and development in the pharmaceutical and agrochemical sectors due to its unique structural features. It is primarily sought after by R&D chemists and process development scientists for constructing complex molecular architectures, particularly in the synthesis of active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the chlorophenyl and nitrile functionalities.
• Material Science: Serves as a precursor for specialty polymers and advanced organic materials with specific electronic or mechanical properties.
• Academic & Contract Research: Essential reagent for methodological studies in organic synthesis, including ring-forming reactions and functional group transformations.
• Chemical Library Synthesis: Employed in combinatorial chemistry and high-throughput screening to generate diverse compound libraries for biological testing.

Basic Information

Product Name	4-(3-Chlorophenyl)-Tetrahydro-2H-Pyran-4-Carbonitrile
CAS No.	473706-22-8
Molecular Formula	C12H12ClNO
Molecular Weight	221.68 g/mol
Synonyms	4-(3-Chlorophenyl)tetrahydro-2H-pyran-4-carbonitrile; 4-(3-Chlorophenyl)oxane-4-carbonitrile; 4-(3-Chlorophenyl)tetrahydropyran-4-carbonitrile; 4-(m-Chlorophenyl)tetrahydro-2H-pyran-4-carbonitrile; 4-(3-Chlorophenyl)-4-cyanotetrahydropyran; 4-Cyano-4-(3-chlorophenyl)tetrahydropyran; 4-(3-Chlorophenyl)-4-cyanotetrahydro-2H-pyran
EINECS	Contact for details

Quality Control

Our 4-(3-Chlorophenyl)-Tetrahydro-2H-Pyran-4-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to cGMP principles and ISO standards guarantees a reliable supply of high-purity material for your critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.