Description

5-Methoxy-2-Nitro-4-Trifluoromethyl-Phenylamine is a high-purity, specialized aromatic amine derivative featuring methoxy, nitro, and trifluoromethyl substituents. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block for the synthesis of complex organic molecules. It is primarily utilized by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drug candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging the biological activity imparted by its unique substitution pattern.
• Dye and Pigment Manufacturing: Serves as a building block for the production of specialized dyes, pigments, and colorants, where the nitro and amine groups are essential for chromophore development.
• Material Science Research: Employed in the development of advanced polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing and donating functional groups.
• Chemical Research & Development: A valuable reagent for organic synthesis, including palladium-catalyzed cross-coupling reactions, reduction reactions, and functional group transformations in academic and industrial labs.

Basic Information

Product Name	5-Methoxy-2-Nitro-4-Trifluoromethyl-Phenylamine
CAS No.	473537-32-5
Molecular Formula	C9H9F3N2O3
Molecular Weight	250.18 g/mol
Synonyms	2-Nitro-5-methoxy-4-(trifluoromethyl)aniline; 4-Amino-2-nitro-5-(trifluoromethyl)anisole; 5-Methoxy-2-nitro-4-(trifluoromethyl)benzenamine; 4-(Trifluoromethyl)-2-nitro-5-methoxyaniline; 2-Nitro-4-trifluoromethyl-5-methoxyaniline; 5-Methoxy-2-nitro-α,α,α-trifluoro-p-toluidine; Benzenamine, 5-methoxy-2-nitro-4-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 5-Methoxy-2-Nitro-4-Trifluoromethyl-Phenylamine is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in light-resistant secondary packaging. For long-term storage, consider an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.