Description

5-Silaspiro[4.4]Nonane-2-Carboxylicacid,3-Amino-,(2R,3S)-Rel-(9Ci) is a high-purity, stereochemically defined silaspiro compound that serves as a sophisticated chiral building block in advanced organic synthesis. Its unique spirocyclic silicon-containing framework and dual functional groups make it a critical intermediate for constructing complex molecular architectures with precise spatial orientation. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and metabolic disease therapeutic areas.
• Agrochemical Synthesis: Used in the creation of novel, high-performance pesticides and herbicides where the silaspiro structure confers unique biological activity and stability.
• Organosilicon Chemistry Research: A valuable substrate for studying novel silicon-carbon bond formations and the properties of spirocyclic silicon compounds.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Precursor: Potential building block for advanced silicon-based polymers and hybrid organic-inorganic materials with specialized properties.

Basic Information

Product Name	5-Silaspiro[4.4]Nonane-2-Carboxylicacid,3-Amino-,(2R,3S)-Rel-(9Ci)
CAS No.	472966-20-4
Molecular Formula	C9H17NO2Si
Molecular Weight	199.32 g/mol
Synonyms	(2R,3S)-3-Amino-5-silaspiro[4.4]nonane-2-carboxylic acid; rel-(2R,3S)-3-Amino-5-silaspiro[4.4]nonane-2-carboxylic acid; 3-Amino-5-silaspiro[4.4]nonane-2-carboxylic acid, (2R,3S)-rel-; 5-Silaspiro[4.4]nonane-2-carboxylic acid, 3-amino-, (2R,3S)-rel-; Chiral Silaspiro Amino Acid; Silicon-containing Spirocyclic Amino Acid; CAS 472966-20-4
EINECS	Contact for details

Quality Control

Every batch of 5-Silaspiro[4.4]Nonane-2-Carboxylicacid,3-Amino-,(2R,3S)-Rel-(9Ci) is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and enantiomeric purity suitable for demanding R&D applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and compliance with your research protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.