Description

Cyclohexanecarboxylic Acid, 2-(Hydroxyimino)-1-Methyl-, Ethyl Ester, (1R,2E)- is a high-purity, stereochemically defined chiral intermediate of significant importance in modern synthetic chemistry. Its value lies in its role as a key building block for the synthesis of complex, biologically active molecules, offering precise control over the final product's three-dimensional structure. This compound is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and other fine chemicals where stereochemical integrity is critical.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon in the research and development of new drug candidates, particularly for constructing complex molecular architectures.
• Agrochemical Synthesis: Used in the production of advanced, stereoselective pesticides and herbicides where specific isomer activity is required.
• Asymmetric Catalysis Research: Serves as a substrate or ligand precursor in the development of new catalytic systems for stereoselective transformations.
• Fine Chemical Manufacturing: Employed in the synthesis of specialty chemicals, flavors, and fragrances that demand high enantiomeric purity.
• Academic & R&D Laboratories: A valuable tool for methodological studies in organic synthesis and medicinal chemistry.

Basic Information

Product Name	Cyclohexanecarboxylic Acid, 2-(Hydroxyimino)-1-Methyl-, Ethyl Ester, (1R,2E)-
CAS No.	472961-96-9
Molecular Formula	C11H19NO3
Molecular Weight	213.27 g/mol
Synonyms	(1R,2E)-2-(Hydroxyimino)-1-methylcyclohexanecarboxylic acid ethyl ester; Ethyl (1R,2E)-2-(hydroxyimino)-1-methylcyclohexanecarboxylate; (1R,2E)-Ethyl 2-(hydroxyimino)-1-methylcyclohexanecarboxylate; (1R,2E)-1-Methyl-2-(hydroxyimino)cyclohexanecarboxylic Acid Ethyl Ester; (R,E)-Ethyl 1-methyl-2-(hydroxyimino)cyclohexanecarboxylate; Chiral Oxime Ester Intermediate
EINECS	Contact for details

Quality Control

Our Cyclohexanecarboxylic Acid, 2-(Hydroxyimino)-1-Methyl-, Ethyl Ester, (1R,2E)- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral HPLC, to ensure high chemical and enantiomeric purity, meeting the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.